Ultrasonic analyte concentration and application in flow cytometry

US10537831B2 · kind B2 · utility

Assignee

• Triad National Security, LLC · US

Inventors

• Gregory Kaduchak · Los Alamos, US
• Greg Goddard · Los Alamos, US
• Gary Salzman · Los Alamos, US
• Dipen N. Sinha · Los Alamos, US
• John C. Martin · Los Alamos, US
• Christopher Kwiatkowski · Los Alamos, US
• Steven Wayde Graves · Santa Fe, US

Key dates

• Filing date: Jun 3, 2015
• Grant date: Jan 21, 2020
• Expiry date: Nov 14, 2037

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10T137/206
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

The present invention includes an apparatus and corresponding method for concentrating analytes within a fluid flowing through a tube using acoustic radiation pressure. The apparatus includes a function generator that outputs a radio frequency electrical signal to a transducer that transforms the radio frequency electric signal to an acoustic signal and couples the acoustic signal to the tube. The acoustic signal is converted within the tube to acoustic pressure that concentrates the analytes within the fluid.