CXCR4 binding molecules and methods of use thereof

US10538596B2 · kind B2 · utility

Assignee

• ADALTA LIMITED · AU

Inventors

• Michael Foley · New York, US
• Andrew James Pow · Burlingame, US
• Katherine Griffiths · Melbourne, AU
• Samantha Cobb · Melbourne, AU
• Katerina Viduka · Melbourne, AU

Key dates

• Filing date: Jan 8, 2016
• Grant date: Jan 21, 2020
• Expiry date: Jan 8, 2036

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2800/323
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present disclosure relates to polypeptides (also referred to herein as CXCR4 binding molecules or polypeptides) that are directed against the G-coupled protein receptor CXCR4, also known as Fusin or CD184. The invention also relates to nucleic acids encoding such polypeptides; to methods for preparing such polypeptide; to compositions, and in particular to pharmaceutical compositions that comprise such polypeptides and to uses of such polypeptides for therapeutic or diagnostic purposes.