Compounds and methods for modulation of DUX4
US10538763B2 · kind B2 · utility
18Cited by
182References
17Claims
0Family size
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Key dates
| Filing date | Jan 15, 2016 |
| Grant date | Jan 21, 2020 |
| Priority date | — |
| Expiry date | Jan 15, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2310/351
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present disclosure pertains generally to double-stranded small interfering RNAs that modulate gene expression for use in research, diagnostics, and/or therapeutics. In certain embodiments, the present disclosure provides double-stranded small interfering RNAs that modulate DUX4 gene expression. In certain embodiments, the present disclosure provides methods of inhibiting DUX4 gene expression by contacting a cell with double-stranded small interfering RNAs.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.