Patent · US Active

Compositions and methods for detecting microorganisms

US10538771B2 · kind B2 · utility

0Cited by
10References
4Claims
0Family size

Assignee

Inventors

Key dates

Filing dateAug 31, 2018
Grant dateJan 21, 2020
Priority date—
Expiry dateAug 31, 2038

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N2333/31
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

Described herein are compositions and methods for detecting the presence or absence of a microorganism in a sample comprising contacting the sample with an aptamer capable of binding to a cell-surface protein of the microorganism to form a complex, contacting the mixture with a second aptamer capable of binding to the first cell-surface protein or a second cell-surface protein of the microorganism; and performing an assay to detect the second aptamer, wherein detecting the second aptamer indicates that the microorganism is present in the sample, and wherein not detecting the second aptamer indicates that the microorganism is absent from the sample.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.