Modulation of a response signal to distinguish between analyte and background signals
US10542918B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Oct 23, 2013 |
| Grant date | Jan 28, 2020 |
| Priority date | — |
| Expiry date | May 8, 2035 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61B5/7203
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
A method for modulating a response signal includes introducing functionalized particles into a lumen of subsurface vasculature, wherein the functionalized particles are configured to interact with one or more target analytes present in blood circulating in the subsurface vasculature; and non-invasively detecting the one or more target analytes. A response signal, which may include a background signal and an analyte response signal related to interaction of the functionalized particles with the one or more target analytes, is transmitted from the subsurface vasculature. A modulation configured to alter the response signal such that the analyte response signal is affected differently than the background signal may be applied to a portion of subsurface vasculature. Analyte detection may be achieved by differentiating the analyte response signal from the background signal.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.