Substituted amines for treating cardiac diseases
US10543212B2 · kind B2 · utility
7Cited by
0References
11Claims
0Family size
Assignee
Inventors
- Nobuyuki Matsunaga
- Takashi Nakahata
- Yuta Tanaka
- Hiroki Takahagi
- Yasufumi Miyamoto
- Rei Okamoto
- Takeshi Yoshikawa
- Yoshito Terao
- Takafumi YUKAWA
- Keiko Kakegawa
- Yoichi Nishikawa
- Terufumi Takagi
- Masashi Takahashi
- Mallareddy Komandla
- Lily Kwok
- Joanne Miura
- Mark Sabat
- Nicholas Scorah
- Paul TANIS
- John Tyhonas
- Phong Vu
- Haixia Wang
- Xiaolun Wang
- Junya Shirai
- Tomohiro Okawa
- Zenyu Shiokawa
- Akito Shibuya
Key dates
| Filing date | Mar 23, 2018 |
| Grant date | Jan 28, 2020 |
| Priority date | — |
| Expiry date | Mar 23, 2038 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P9/06
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides a compound having a CaMKII inhibitory action, which is expected to be useful as an agent for the prophylaxis or treatment of cardiac diseases (particularly catecholaminergic polymorphic ventricular tachycardia, postoperative atrial fibrillation, heart failure, fatal arrhythmia) and the like.The present invention relates to a compound represented by the formula (I): wherein each symbol is as defined in the specification, or a salt thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.