Polyhydroxylated bile acids for treatment of biliary disorders
US10543220B2 · kind B2 · utility
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2References
12Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 21, 2015 |
| Grant date | Jan 28, 2020 |
| Priority date | — |
| Expiry date | Dec 21, 2035 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07J41/0061
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides, in part, polyhydroxylated bile acids for treating biliary disorders, for example, biliary disorders arising out of cholestasis of portal hypertension. The invention also provides, in part, polyhydroxylated bile acids for stimulating bile flow. New compounds 2α, 3α, 7α, 12α-tetrahydroxy-5β-cholanoic acid and 3α. 4α, 7α, 12α-tetrahydroxy-5β-cholanoic acid are disclosed, uses thereof and synthesis thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.