5-HT2 antagonists
US10544103B2 · kind B2 · utility
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14Claims
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Assignee
Inventor
Key dates
| Filing date | Jun 22, 2016 |
| Grant date | Jan 28, 2020 |
| Priority date | — |
| Expiry date | Jun 22, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D409/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Provided are 1-amidino-3-aryl-2-pyrazoline derivatives which exhibit antagonizing activity towards serotonin 5-HT 2B receptors and pharmaceutical compositions containing these derivatives. Also provided is the use of the compounds as a medicament and for the treatment of fibrosis, cardiovascular diseases, pain, IBD, and other inflammatory diseases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.