Process for the synthesis of amide bonds with the aid of novel catalysts

US10544186B2 · kind B2 · utility

Assignee

• Merck Patent GmbH · DE

Inventors

• Nikolai Mykola Ignatyev · Duisburg, DE
• Walter Frank · Holland, US
• Peter Barthen · Rheinberg, DE
• Myroslav Vysotsky · Ingelheim am Rhein, DE

Key dates

• Filing date: Nov 6, 2017
• Grant date: Jan 28, 2020
• Expiry date: Nov 6, 2037

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K5/06078
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention relates to a process for the production of amide bonds, in particular peptide bonds, with the aid of novel amide linking reagents containing an anion of the formula (I), to the novel reagents, and to the preparation thereof.