Systems and methods for nucleic acid sequencing

US10544456B2 · kind B2 · utility

Assignee

• GENAPSYS, INC. · US

Inventors

• Hesaam Esfandyarpour · Redwood City, US
• Kosar Baghbani Parizi · Redwood City, US
• Saurabh Paliwal · Mountain View, US
• Seth Stern · Palo Alto, US
• Paul Kenney · Sunnyvale, US
• Meysam R. Barmi · Menlo Park, US
• Ali Nabi · Belmont, US
• Hamid Rategh · Cupertino, US

Key dates

• Filing date: Jul 20, 2017
• Grant date: Jan 28, 2020
• Expiry date: Jul 20, 2037

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12Q1/6869
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

Provided herein are systems and methods for processing and analyzing nucleic acids and other biomolecules. Methods may include processing nucleic acid molecules in an emulsion of droplets. Methods of analyzing nucleic acid molecules may include coupling nucleic acids to a bead or other support. Methods may include analysis of nucleic acid molecules using a redox mediator. In some cases, analysis of the nucleic acid molecule includes determining a nucleotide sequence of the nucleic acid molecule.