System and method for real-time MRI-guided object navigation

US10548505B2 · kind B2 · utility

Assignees

• Siemens Healthcare Limited · DE
• THE JOHNS HOPKINS UNIVERSITY · US

Inventors

• Eva Rothgang · Nuremberg, DE
• Arne Hengerer · Steinfeld (Oldenburg), DE
• Lars Lauer · Neunkirchen, DE
• Jan Fritz · Baltimore, US
• Paul A. Bottomley · Clifton Park, US
• Wesley David Gilson · North Beach, US
• Robert Grimm · Nuremberg, DE

Key dates

• Filing date: Mar 15, 2016
• Grant date: Feb 4, 2020
• Expiry date: Dec 6, 2038

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61B2090/374
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

A magnetic resonance method and system are provided for magnetic resonance (MR) image-guided insertion of an object into a biological tissue along a predetermined trajectory. The trajectory provides a path between a starting point and a target site within the tissue. Sufficiently high resolution images can be generated in real time to precisely guide the needle placement. A compressed sensing approach is used to generate the images based on minimization of a cost function, where the cost function is based on the predetermined needle path, artifact effects associated with the needle, the negligible changes in the images away from the trajectory, and the limited differences between successive images. The improved combination of spatial and temporal resolution facilitates an insertion procedure that can be continuously adjusted to accurately follow a predetermined trajectory in the tissue, without interruptions to obtain verification images.