Patent · US Active

Nicotinamide mononucleotide derivatives and their uses

US10548913B2 · kind B2 · utility

12Cited by

17References

29Claims

0Family size

Assignee

Metro International Biotech, LLC · US

Inventors

Karl D. Normington · Prides Crossing, US
David A. Sinclair · Feldkirchen-Westerham, DE
David J. Livingston · Barrington, US
James M. McKearin · Litchfield, US
Bruce Szczepankiewicz · Gages Lake, US
Jonathan N. Kremsky · Worcester, US

Key dates

Filing date	Jan 23, 2018
Grant date	Feb 4, 2020
Priority date	—
Expiry date	Jan 23, 2038

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07H19/04
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention relates to compositions of nicotinamide mononucleotide derivatives and their methods of use. The invention also relates to methods of preparing nicotinamide mononucleotide derivatives. The invention relates to pharmaceutical compositions and nutritional supplements containing a nicotinamide mononucleotide derivative. The invention relates to methods of using nicotinamide mononucleotide derivatives that promote the increase of intracellular levels of nicotinamide adenine dinucleotide (NAD+) in cells and tissues for treating diseases and improving cell and tissue survival.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.