Substituted aromatic compounds and related method for the treatment of fibrosis

US10550066B2 · kind B2 · utility

Assignee

• PROMETIC PHARMA SMT LIMITED · GB

Inventors

• Boulos Zacharie · Keyano, CA
• Shaun Abbott · Rue du Bois des Loges, CA
• Lyne Gagnon · Keyano, CA
• Pierre Laurin · Mount Royal, CA
• Brigitte Grouix · Montréal, CA

Key dates

• Filing date: Apr 4, 2018
• Grant date: Feb 4, 2020
• Expiry date: Apr 4, 2038

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02A50/30
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to compounds of: or a pharmaceutically acceptable salt thereof, wherein A is C5 alkyl, C6 alkyl, C5 alkenyl, C6 alkenyl, C(O)—(CH2)n—CH3 or CH(OH)—(CH2)n—CH3 wherein n is 3 or 4; R1 is H, F or OH; R2 is C5 alkyl, C6 alkyl, C5 alkenyl, C6 alkenyl, C(O)—(CH2)n—CH3 or CH(OH)—(CH2)n—CH3 wherein n is 3 or 4; R3 is H, F, OH or CH2Ph; R4 is H, For OH; Q is