Patent · US Active

Crystal form of brexpiprazole and preparation method therefor

US10550109B2 · kind B2 · utility

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Key dates

Filing dateMay 12, 2017
Grant dateFeb 4, 2020
Priority date
Expiry dateMay 12, 2037

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07B2200/13
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Disclosed are a crystal form of brexpiprazole and a preparation method therefor. The X-ray powder diffraction pattern, which is detected with Cu—Kα radiation, of the crystal form of brexpiprazole has characteristic peaks at the positions where 2θ is about 9.1±0.2, 15.2±0.2, 15.7±0.2, 17.6±0.2, 18.1±0.2, 24.4±0.2. The crystal form I of brexpiprazole has a high purity, good stability and good reproducibility, and is suitable for industrial production.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.