Viral replication inhibitors

US10550123B2 · kind B2 · utility

Assignee

• Katholieke Universiteit Leuven, KU LEUVEN R&D · BE

Inventors

• Dorothée Alice Marie-Eve Bardiot · Leuven, BE
• Gunter Carlens · Leuven, BE
• Kai Dallmeier · Kessel-Lo, BE
• Suzanne Kaptein · Leuven, BE
• Michael McNaughton · Leuven, BE
• Arnaud Marchand · Leuven, BE
• Johan Neyts · Namur, BE
• Wim Smets · Leuven, BE
• Mohamed Koukni · Leuven, BE

Key dates

• Filing date: Sep 26, 2012
• Grant date: Feb 4, 2020
• Expiry date: Sep 26, 2032

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02A50/30
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present invention relates to a series of novel compounds, methods to prevent or treat viral infections in animals by using the novel compounds and to said novel compounds for use as a medicine, more preferably for use as a medicine to treat or prevent viral infections, particularly infections with RNA viruses, more particularly infections with viruses belonging to the family of the Flaviviridae, and yet more particularly infections with the Dengue virus. The present invention furthermore relates to pharmaceutical compositions or combination preparations of the novel compounds, to the compositions or preparations for use as a medicine, more preferably for the prevention or treatment of viral infections. The invention also relates to processes for preparation of the compounds.