Patent · US Active

C,O-spiro aryl glycoside compounds, preparation therefor and use thereof

US10550143B2 · kind B2 · utility

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20Claims

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Assignee

SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES · CN

Inventors

Hong Liu · Shanghai, CN
Jia-He Li · Cockeysville, US
Jiang Wang · Shanghai, CN
Jingya Li · Gothenburg, SE
Hui-Ping Chen · Taoyuan, TW
Dan Li · Shoreview, US
Jian Li · Shanghai, CN
Yibing Wang · Pasadena, US
Hualiang Jiang · Shanghai, CN
Kaixian Chen · Shanghai, CN

Key dates

Filing date	Jun 23, 2016
Grant date	Feb 4, 2020
Priority date	—
Expiry date	Sep 25, 2036

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D493/10
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

C, O-spiro aryl glycoside compounds are provided. Specifically provided are C, O-spiro aryl glycoside compounds represented by the formula (I), wherein the definitions of each variable group are described in the specification. Also provided are methods of preparing and using the C, O-spiro aryl glycoside compounds. The C, O-spiro aryl glycoside compounds can be used as SGLT2 inhibitors and for treating diseases, such as diabetes, atherosclerosis, and adiposity.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.