Patent · US Active

Humanized antibodies against CEACAM1

US10550196B2 · kind B2 · utility

1Cited by
47References
16Claims
0Family size

Assignee

Inventors

Key dates

Filing dateApr 27, 2015
Grant dateFeb 4, 2020
Priority date
Expiry dateAug 13, 2035

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N2333/70503
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Humanized antibodies, capable of specific binding to human CEACAM1 molecules containing human-to-murine back-mutations in non-CDR variable regions, and their encoding polynucleotide sequences are provided. Pharmaceutical compositions comprising these antibodies as well as methods of their use in treating and diagnosing cancer and other conditions are also provided.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.