High resolution photoacoustic imaging in scattering media using structured illumination

US10551357B2 · kind B2 · utility

Assignees

• The Regents of the University of Colorado, a Body Corporate · US
• Research Center for Non Destructive Testing GmbH · AT
• UNIVERSITÄT INNSBRUCK · AT

Inventors

• Todd W. Murray · Golden, US
• Peter Burgholzer · Linz, AT
• Markus Haltmeier · Innsbruck, AT

Key dates

• Filing date: Sep 28, 2017
• Grant date: Feb 4, 2020
• Expiry date: Sep 28, 2037

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2201/106
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

A method for high resolution photoacoustic imaging in scattering media using structured illumination may include illuminating a sample of an absorption object with structured illumination, including illuminating the sample with multiple different speckle patterns at different times. The method may also include detecting multiple photoacoustic signals generated by the absorption object in response to illumination with the different speckle patterns to generate multiple photoacoustic responses. The method may also include reconstructing an absorber distribution of the absorption object by exploiting joint sparsity of sound sources in the plurality of photoacoustic responses.