Compositions and methods for entrapping protein on a surface
US10556218B2 · kind B2 · utility
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8Claims
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Assignee
Inventor
Key dates
| Filing date | Oct 8, 2018 |
| Grant date | Feb 11, 2020 |
| Priority date | — |
| Expiry date | Oct 8, 2038 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01J2219/00725
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention provides a formulation to link protein to a solid support that comprises one or more proteins, Oligo-dT and one or more non-volatile, water-soluble protein solvents, solutes or combination thereof in an aqueous solution. Further provided is a method of attaching a protein to a surface of a substrate. The formulations provided herein are contacted onto the substrate surface, printed thereon and air dried. The substrate surface is irradiated with UV light to induce thymidine photochemical crosslinking via the thymidine moieties of the Oligo-dT.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.