Indazolyl-1,2,4-thiadiazolamines and related compounds for inhibition of Rho-associated protein kinase and the treatment of disease
US10556898B2 · kind B2 · utility
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Key dates
| Filing date | Feb 14, 2019 |
| Grant date | Feb 11, 2020 |
| Priority date | — |
| Expiry date | Feb 14, 2039 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F9/65583
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides indazolyl thiadiazolamines and related compounds, pharmaceutical compositions, methods of inhibiting Rho-associated protein kinase, and methods of treating inflammatory disorders, immune disorders, fibrotic disorders, and other medical disorders using such compounds. An exemplary indazolyl thiadiazolamine compound is an N-(3-(5-((1H-indazol-5-yl)amino)-1,2,4-thiadiazol-3-yl)phenyl)-heteroaryl-carboxamide compound.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.