N-(substituted-phenyl)-sulfonamide derivatives as kinase inhibitors
US10561660B2 · kind B2 · utility
4Cited by
1References
7Claims
0Family size
Inventors
Key dates
| Filing date | Jun 19, 2017 |
| Grant date | Feb 18, 2020 |
| Priority date | — |
| Expiry date | Jun 19, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D513/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to N-(substituted-phenyl)-sulfonamide compounds, which are extremely useful as inhibitors of protein kinases (e.g. PERK kinase) and accordingly can be used for the treatment of cell proliferative disorders, such as cancer, or diseases associated with activated unfolded protein response pathways, such as Alzheimer's disease. The present invention also provides methods for preparing these compounds, pharmaceutical compositions comprising these compounds, and methods of treating diseases utilizing pharmaceutical compositions comprising these compounds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.