System for manufacturing fiber scaffolds for use in tracheal prostheses
US10562225B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | Dec 15, 2014 |
| Grant date | Feb 18, 2020 |
| Priority date | — |
| Expiry date | Oct 11, 2035 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB29K2311/00
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
A system for manufacturing a synthetic organ suitable for transplantation into a biological organism is provided. This synthetic organ includes a three-dimensional polymer scaffold, wherein the shape and dimensions of the polymer scaffold are based on a native organ, wherein the polymer scaffold further includes at least one layer of polymer fibers that have been deposited by electrospinning, and wherein the orientation of the fibers in the scaffold relative to one another is generally parallel, random, or both; and wherein the polymer scaffold has been preseeded with at least one type of biological cell prior to implantation into a biological organism, and wherein the at least one type of biological cell is operative to facilitate integration of the polymer scaffold into the organism so that the polymer scaffold may function in a manner significantly similar to or the same as the native organ.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.