Albumin-purification method comprising a nanofiltration step, solution, and composition for therapeutic use containing the same
US10562957B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Feb 27, 2017 |
| Grant date | Feb 18, 2020 |
| Priority date | — |
| Expiry date | Aug 24, 2037 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to an albumin-purification method comprising a step consisting in subjecting an aqueous albumin solution, with a concentration of between 15 g/l and 80 g/l and a pH of not less than 7, to nanofiltration in a temperature range of between 15 DEG C. and 55 DEG C. The invention also relates to: a virally-safe aqueous albumin solution which can be obtained using the inventive method and in which the sites for the transport and binding of the active therapeutic ingredients of the albumin are available; and an albumin composition for therapeutic use, which is obtained by adapting the albumin solution that is intended for clinical use.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.