Patent · US Active

Ligand-cytotoxic drug conjugate, preparation method thereof, and uses thereof

US10562977B2 · kind B2 · utility

0Cited by

13References

28Claims

0Family size

Assignees

SHANGHAI HENGRUI PHARMACEUTICAL CO., LTD. · CN
JIANGSU HENGRUI MEDICINE CO., LTD. · CN

Inventors

Yali Wang · Lianyungang, CN
Lianshan Zhang · 安丰镇, CN
Jindong LIANG · Shanghai, CN
Ang Li · Beijing, CN
Fanglong Yang · Shanghai, CN

Key dates

Filing date	Jan 22, 2015
Grant date	Feb 18, 2020
Priority date	—
Expiry date	May 25, 2036

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K16/32
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Ligand-cytotoxic drug conjugates, pharmaceutical compositions, preparation methods, and pharmaceutical uses thereof are provided. More specifically, a ligand-cytotoxic drug conjugate of general formula Pc-(X-Y-D)n is provided. The ligand-cytotoxic drug conjugate can be used to treat cancer via receptor modulation.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.