Patent · US Active

Manufacture of active highly phosphorylated human lysosomal sulfatase enzymes and uses thereof

US10563183B2 · kind B2 · utility

2Cited by
11References
18Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJan 12, 2018
Grant dateFeb 18, 2020
Priority date
Expiry dateJan 18, 2038

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N2800/04
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

This invention provides compositions of active highly phosphorylated lysosomal sulfatase enzymes, their pharmaceutical compositions, methods of producing and purifying such lysosomal sulfatase enzymes and compositions and their use in the diagnosis, prophylaxis, or treatment of diseases and conditions, including particularly lysosomal storage diseases that are caused by, or associated with, a deficiency in the lysosomal sulfatase enzyme.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.