Rapid characterization of the solubility of amphiphiles

US10564084B2 · kind B2 · utility

Assignees

• THE TRUSTEES OF PRINCETON UNIVERSITY · US
• CNRS-CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE · FR
• UNIVERSITE DE RENNES · FR
• CHANCELLOR, MASTERS & SCHOLARS OF UNIV. OF OXFORD · GB

Inventors

• Matthieu Roche · Paris, FR
• Howard A. Stone · Princeton, US
• Isabelle Cantat · Rennes, FR
• Arnaud Saint-Jalmes · Olivet, FR
• Ian Griffiths · Felton, GB
• Sebastien Le Roux · Brest, FR
• Zhen Zhen Li · Paris, FR

Key dates

• Filing date: Jan 30, 2014
• Grant date: Feb 18, 2020
• Expiry date: Jun 17, 2037

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2015/0003
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

Disclosed is a process and device allowing for fast measurements of the physicochemical properties of amphiphiles (lipids, surfactants, soaps, . . . ). A Marangoni flow is created and characterized using amphiphiles to be characterized. The observed flow is characterized, and using the disclosed process, one can deduce from this measurement many important physicochemical parameters of the amphiphiles such as their critical micellar concentration. Compared to existing techniques, the disclosed process offers the advantage that it requires a single experiment to deduce the parameters, when other techniques (pendant drop method, conductometry, etc . . . ) require the measurement of a quantity (interfacial tension, conductometry) against a systematically varied parameter (amphiphile concentration, . . . ). The disclosed process and devices are ideal to characterize and/or screen rapidly amphiphiles molecules based on their interaction with a solvent.