Self assembled gels for controlled delivery of encapsulated agents to cartilage
US10568840B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | May 8, 2017 |
| Grant date | Feb 25, 2020 |
| Priority date | — |
| Expiry date | Sep 11, 2037 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61M31/002
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A self-assembled gel composition with enhanced adhesion to cartilage tissue is provided. A cationic agent co-self assembles with a generally regarded as safe (GRAS), low molecular weight (<2,500 Da) gelator, forming homogeneous self-supporting gel that can encapsulate one or more therapeutic agents for controlled release. The composition adheres to connective tissue, e.g., cartilage, to a greater extent and a greater length of time than a self-assembled gel from gelators alone. The composition is used to specifically target connective tissue and deliver one or more therapeutic, prophylactic, or diagnostic agents for controlled release to improve dosing efficacy.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.