Substituted pyrrolopyrimidine CDK inhibitor, pharmaceutical composition containing same and use thereof
US10570141B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Mar 27, 2017 |
| Grant date | Feb 25, 2020 |
| Priority date | — |
| Expiry date | Mar 27, 2037 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P35/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention belongs to the field of pharmaceutical chemistry, and relates to a substituted pyrrolopyrimidine CDK inhibitor, in particular to a compound as shown in formula I or a pharmaceutically acceptable salt or solvate thereof, as well as a preparation method thereof and a pharmaceutical composition thereof. The present invention also relates to the use of the compound and the pharmaceutical composition thereof in the preparation of a drug for treating diseases associated with CDK inhibition. The compound according to the present invention has a marked inhibitory effect on CDK, excellent drug absorption and significantly superior oral absorption effect.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.