Process for producing at least one metabolite of interest by conversion of a pentose in a microorganism
US10570423B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Nov 19, 2015 |
| Grant date | Feb 25, 2020 |
| Priority date | — |
| Expiry date | Nov 19, 2035 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P7/18
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Disclosed is a process for producing at least one metabolite of interest by conversion of a pentose in a microorganism. The process includes at least: (i) an operation of culturing a recombinant microorganism expressing a synthetic pathway for pentose assimilation which includes at least the following steps: a) phosphorylation in position 1 of a pentose chosen from (D)-xylulose and/or (L)-ribulose, b) cleavage of the pentose-1-phosphate obtained at the end of step a), in order to obtain glycolaldehyde and dihydroxyacetone phosphate (DHAP), and (ii) an operation of recovering the at least one metabolite of interest obtained at the end of the culturing operation (i). Also disclosed is an associated microorganism.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.