Patent · US Active

Apparatus and method for determining the mechanical properties of cells

US10571387B2 · kind B2 · utility

0Cited by

4References

19Claims

0Family size

Assignee

Zellmechanik Dresden GmbH · DE

Inventors

Jochen Guck · Leipzig, DE
Oliver Otto · Kelmis, BE
Philipp Rosendahl · Dresden, DE

Key dates

Filing date	Jun 26, 2014
Grant date	Feb 25, 2020
Priority date	—
Expiry date	May 9, 2036

Classification

Technology area (CPC G)Physics
CPC primaryG01N15/149
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

The present invention relates to a method and an apparatus for sorting cells. The apparatus for determining the mechanical properties of cells comprises: —a microfluidic channel having an inlet and an outlet, the channel being configured to let a fluid containing cells pass therethrough, —a means for introducing a fluid containing cells into the channel so as to establish a flow of the fluid within the channel, —a cell shape measurement device arranged to obtain information of a deformed shape of a cell deformed due to the flow pattern created by the interaction of the fluid flow with the channel, and —an analysis means arranged to use data from the cell shape measurement device to obtain mechanical properties of the cells.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.