Navigated transcranial magnetic stimulation planning using a structural effectiveness index
US10576296B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Mar 23, 2015 |
| Grant date | Mar 3, 2020 |
| Priority date | — |
| Expiry date | Aug 30, 2036 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61N2/02
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
Described herein are methods including determining a structural effectiveness index (SEI) for a target area of a brain which accounts for the effectiveness of a Transcranial Magnetic Stimulation (TMS) pulse based on at least one neurological feature of the brain. An SEI may include an anisotropy index (AI). An AI may account for the effectiveness of a TMS pulse based at least on the local anisotropy of the target area. An SEI may include a connectivity index (CI). A CI may account for the effectiveness of a TMS pulse at a different location of the brain than a stimulated target area. Moreover, the CI can be based at least partially on white matter tract connections. The SEI of at least one area of a brain may be used in order to plan a minimum effective dose at that location based on the actual neurological structure there, e.g. the anisotropy or white matter tracts at that area.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.