Patent · US Active

Sodium channel modulators

US10577308B2 · kind B2 · utility

0Cited by

4References

5Claims

0Family size

Assignees

The Florey Institute · AU
The University of Melbourne · AU

Inventors

Spencer John Williams · Berkeley, US
Bevyn Jarrott · Melbourne, AU

Key dates

Filing date	Mar 24, 2016
Grant date	Mar 3, 2020
Priority date	—
Expiry date	Mar 24, 2036

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D403/12
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present disclosure relates generally to compounds having activity as voltage-gated sodium channel blockers and their use in the field of therapeutic treatment, including the therapy or management of conditions associated with excessive, unwanted, inadequate or otherwise undesirable sodium ion passage through cellular membranes via voltage-gated sodium channels. In some embodiments, the disclosure relates to aryloxy-substituted amines for use as sodium channel blockers or modulators. Methods for their manufacture and compositions containing the compounds are also disclosed.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.