Galunisertib crystalline form, preparation method thereof and use thereof
US10577372B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jul 21, 2017 |
| Grant date | Mar 3, 2020 |
| Priority date | — |
| Expiry date | Jul 21, 2037 |
Classification
- Technology area (CPC —)General
Abstract
The present disclosure relates to a novel crystalline form of Galunisertib, processes for preparation and use thereof. The present disclosure also relates to a pharmaceutical composition comprises the novel crystalline form of Galunisertib and use of the novel crystalline form of Galunisertib and pharmaceutical composition for preparing drugs treating disease. The crystalline form of the present disclosure has good stability, solubility and hygroscopicity, which has significant value for future drug optimization and development.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.