Selective photoactivation of amino acids for single step peptide coupling
US10577391B2 · kind B2 · utility
0Cited by
5References
14Claims
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Key dates
| Filing date | Jun 26, 2018 |
| Grant date | Mar 3, 2020 |
| Priority date | — |
| Expiry date | Jun 26, 2038 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/55
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Disclosed herein are formulations, substrates, and arrays for amino acid and peptide synthesis on microarrays. In certain embodiments, methods for manufacturing and using the formulations, substrates, and arrays including one-step coupling, e.g., for synthesis of peptides in a C→N orientation are disclosed. In some embodiments, disclosed herein are formulations and methods for high efficiency coupling of biomolecules to a substrate.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.