Biochemical sensing using microbubbles on a chip using whispering gallery mode resonance
US10578594B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Dec 27, 2017 |
| Grant date | Mar 3, 2020 |
| Priority date | — |
| Expiry date | May 29, 2038 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG02B6/29341
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A sensing and analysis system on a chip for sensing and analyzing chemical or biological analytes includes a chromatography column having an inlet and an outlet formed on the chip for temporal separation of components of analytes and at least one whispering gallery mode (WGM) optical resonator for sensing of the components. The chromatography column is formed on a first wafer layer. Each WGM optical resonator includes a hollow sealed enclosure formed at or over the inlet or the outlet of or elsewhere along the chromatography column such that a gas flowing through the chromatography column fills the hollow sealed enclosure. Each WGM optical resonator further includes an optical waveguide aligned with the sealed hollow enclosure for evanescent wave light coupling.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.