Automated identification of assay areas in a microfluidic device and detection of assay positive areas based on rate of change of image light intensity
US10578630B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | Dec 9, 2015 |
| Grant date | Mar 3, 2020 |
| Priority date | — |
| Expiry date | Apr 14, 2038 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2201/0635
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Methods are provided for the automated detection of assay-positive assay areas in a microfluidic device. When assays are performed in a microfluidic device, the configuration of the microfluidic circuit and its constituent circuit elements can determine where the reagents/analytes used in the assay can be located within the microfluidic circuit. Methods are provided for automatic identification of the size and shape of the assay areas based on a number of parameters which may include type of assay involved, shape and dimensions of microfluidic circuit elements, velocity and physical characteristics of the fluidic medium within the microfluidic circuit, physical/chemical properties of the analytes/reagents, and/or the number of cells being assayed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.