Method for preventing or treating diseases associated with the inhibition of EGFR

US10583111B2 · kind B2 · utility

Assignee

• ONQUALITY PHARMACEUTICALS CHINA LTD. · CN

Inventors

• Shiyi Zhang · Lake Forest, US
• Zhaoyu Wu · Shanghai, CN
• Chao Liu · Nantong, CN
• Leying Chen · Shanghai, CN
• Xin Zhao · Austin, US
• Zhehui Gong · Shanghai, CN
• Rui Xing · Hubei, CN
• Songxuan Sun · Shanghai, CN
• Jie Luo · Seattle, US

Key dates

• Filing date: May 28, 2019
• Grant date: Mar 10, 2020
• Expiry date: May 28, 2039

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P17/14
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present application provides a use of a nitric oxide releasing agent in preparing a medicament, wherein the medicament is used for preventing or treating EGFR inhibition associated epithelial diseases in a subject. The present application further provides a pharmaceutical composition or a kit comprising EGFR inhibitor and nitric oxide releasing agent.