Compositions comprising urolithins and uses thereof for the stimulation of insulin secretion

US10583114B2 · kind B2 · utility

Assignees

• CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE · FR
• University of Parma · IT
• Ecole Nationale Superieure de Chimie
• Universite De Montpellier · FR

Inventors

• Gerard Cros · Montpellier, FR
• Alan Crozier · Glasgow, GB
• Margherita Dall'asta · Parma, IT
• Daniele Del Rio · Parma, IT
• Richard Magous · Lunel, FR
• Catherine Oiry · Pignan, FR

Key dates

• Filing date: Oct 15, 2014
• Grant date: Mar 10, 2020
• Expiry date: Oct 15, 2034

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A23V2002/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to a composition comprising urolithin A, urolithin B, urolithin C, urolithin D, or a combination thereof, for the stimulation of insulin secretion, and to the use of a compound chosen among urolithin A, urolithin B, urolithin C, urolithin D, or a combination thereof, intended for the stimulation of insulin secretion. The present invention also relates to a composition comprising an effective amount of urolithin B, urolithin C, urolithin D, or a combination thereof, for the treatment or the prevention of diabetes mellitus, and in particular for the treatment or the prevention of type 2 diabetes, and to the use of a compound chosen among urolithin B, urolithin C, urolithin D, and a combination thereof, intended for the treatment or the prevention of diabetes mellitus, and in particular of type 2 diabetes.