Patent · US Active

Anti-epidermal growth factor receptor (EGFR) antibodies

US10584171B2 · kind B2 · utility

1Cited by
46References
76Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 29, 2015
Grant dateMar 10, 2020
Priority date
Expiry dateMay 29, 2035

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N2333/71
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Provided are anti-epidermal growth factor receptor (EGFR) antibodies, aglycosylated CDR-H2 anti-EGFR antibodies, and antigen binding fragments thereof. Also provided are isolated nucleic acid molecules that encode the anti-EGFR antibodies or antigen binding fragments thereof, related expression vectors, and host cells. Provided are methods of making anti-epidermal growth factor receptor (EGFR) antibodies, aglycosylated CDR-H2 anti-EGFR antibodies, and antigen binding fragments thereof. Also provided are related pharmaceutical compositions and methods of their use to treat subjects.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.