Vectors conditionally expressing therapeutic proteins, host cells comprising the vectors, and uses thereof
US10584351B2 · kind B2 · utility
1Cited by
1References
30Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 13, 2017 |
| Grant date | Mar 10, 2020 |
| Priority date | — |
| Expiry date | Jul 13, 2037 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention relates to the field of therapeutics. Most specifically, the invention provides methods of generating conditionally expressing vectors for one or more immuunomodulators under the control of a gene expression modulation system in the presence of activating ligand and uses for therapeutic purposes in animals. These vector may be provided to treat a variety of disorders, e.g., neoplastic disorders, through direct injection or through in vitro engineered cells, such as dendritic cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.