Camptothecin derivatives as anti-HIV agents and methods of identifying agents that disrupt Vif self-association
US10588902B2 · kind B2 · utility
2Cited by
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2Claims
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Assignee
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Key dates
| Filing date | Jun 24, 2014 |
| Grant date | Mar 17, 2020 |
| Priority date | — |
| Expiry date | Jun 7, 2035 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2500/10
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to the use of camptothecin derivatives as anti-HIV agents that disrupt self-association of the viral infectivity factor (Vif) found in HIV and other retroviruses. The present invention also relates to methods of identifying agents that disrupt VIf self-association and methods of using these agents, including methods of treating or preventing HIV infection.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.