Patent · US Active

Processes for the preparation of cis-4-[2-{[(3S,4R)-3-fluorooxan-4-yl]amino}-8-(2,4,6-trichloroanilino)-9H-purin-9-yl]-1-methylcyclohexane-1-carboxamide

US10590136B2 · kind B2 · utility

0Cited by

22References

21Claims

0Family size

Assignee

CELGENE CORPORATION · US

Inventors

Zheng Chen · Los Angeles, US
Maryll E. Geherty · Pennington, US
Matthew Michael Kreilein · Fryeburg, US
Xiaoling Lu · Whippany, US
Nanfei Zou · Fanwood, US

Key dates

Filing date	Oct 3, 2018
Grant date	Mar 17, 2020
Priority date	—
Expiry date	Oct 3, 2038

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P35/00
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

Provided herein are processes for the preparation of cis-4-[2-{[(3S,4R)-3-fluorooxan-4-yl]amino}-8-(2,4,6-trichloroanilino)-9H-purin-9-yl]-1-methylcyclohexane-1-carboxamide, alternatively named (1s,4s)-4-(2-(((3S,4R)-3-fluorotetrahydro-2H-pyran-4-yl)amino)-8-((2,4,6-trichlorophenyl)amino)-9H-purin-9-yl)-1-methylcyclohexane-1-carboxamide, or a salt, solvate, hydrate, or isotopologue thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.