Patent · US Active

Modular DNA-binding domains and methods of use

US10590175B2 · kind B2 · utility

0Cited by

45References

9Claims

0Family size

Inventors

Ulla Bonas · Bodenwerder, DE
Jens Boch · Wunstorf, DE
Sebastian Schornack · Cambridge, GB
Thomas Lahaye · Usingen, DE

Key dates

Filing date	Oct 4, 2017
Grant date	Mar 17, 2020
Priority date	—
Expiry date	Oct 4, 2037

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Q2563/119
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

The present invention refers to methods for selectively recognizing a base pair in a DNA sequence by a polypeptide, to modified polypeptides which specifically recognize one or more base pairs in a DNA sequence and, to DNA which is modified so that it can be specifically recognized by a polypeptide and to uses of the polypeptide and DNA in specific DNA targeting as well as to methods of modulating expression of target genes in a cell.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.