Patent · US Active

Chimeric antigen receptor compositions

US10590205B2 · kind B2 · utility

2Cited by

3References

17Claims

0Family size

Assignee

City of Hope · US

Inventors

John C. Williams · Duarte, US
Christine E. Brown · Duarte, US

Key dates

Filing date	Feb 15, 2017
Grant date	Mar 17, 2020
Priority date	—
Expiry date	Feb 15, 2037

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2319/70
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

Provided herein are compositions, which exhibit diagnostic capabilities and allow to rapidly add functionality to adoptive immunotherapy. The compositions include isolated nucleic acids encoding proteins including antibody regions capable of binding compounds including a peptidyl moiety (e.g., a meditope). The recombinant proteins provided herein are useful, inter alia, for a broad variety of therapeutic and diagnostic purposes. For example, the recombinant proteins provided herein including embodiments thereof may be used as non-invasive means to characterize chimeric antigen receptor (CAR) T cells before and/or during treatment of diseases (e.g., cancer).

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.