Patent · US Active

C5a binding nucleic acids

US10590424B2 · kind B2 · utility

0Cited by

8References

17Claims

0Family size

Assignee

NOXXON Pharma AG · DE

Inventors

Kai Hohlig · Berlin, DE
Axel Vater · Berlin, DE
Klaus Buchner · Schaffhausen, CH
Christian Maasch · Berlin, DE
Sven Klussmann · Berlin, DE

Key dates

Filing date	Dec 12, 2016
Grant date	Mar 17, 2020
Priority date	—
Expiry date	Dec 12, 2036

Classification

Technology area (CPC G)Physics
CPC primaryG01N2333/4716
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention is related to a nucleic acid molecule capable of binding to human C5a, wherein the nucleic acid molecule comprises a central stretch of nucleotides, wherein the central stretch of nucleotides comprises a nucleotide sequence of 5′ AUGn1GGUGKUn2n3RGGGHUGUKGGGn4Gn5CGACGCA 3′ [SEQ ID NO: 61], wherein n1 is U or dU, n2 is G or dG, n3 is A or dA, n4 is U or dU, n5 is U or dU and G, A, U, C, H, K, and R are ribonucleotides, and dU, dG and dA are 2′-deoxyribonucleotides.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.