Diagnosis of fetal abnormalities using polymorphisms including short tandem repeats
US10591391B2 · kind B2 · utility
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183References
17Claims
0Family size
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Key dates
| Filing date | Mar 14, 2013 |
| Grant date | Mar 17, 2020 |
| Priority date | — |
| Expiry date | Mar 27, 2033 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG16B20/00
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention provides systems, apparatuses, and methods to detect the presence of fetal cells when mixed with a population of maternal cells in a sample and to test fetal abnormalities, i.e. aneuploidy. In addition, the present invention provides methods to determine when there are insufficient fetal cells for a determination and report a non-informative case. The present invention involves quantifying regions of genomic DNA from a mixed sample. More particularly the invention involves quantifying DNA polymorphisms from the mixed sample.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.