Patent · US Active

Stable, concentrated radionuclide complex solutions

US10596278B2 · kind B2 · utility

11Cited by

7References

25Claims

0Family size

Assignee

ADVANCED ACCELERATOR APPLICATIONS (ITALY) SRL · IT

Inventors

Francesco de Palo · Cascine Campassa di Sopra, IT
Lorenza Fugazza · Cascine Campassa di Sopra, IT
Donato Barbato · Biella, IT
Maurizio Mariani · Biella, IT
Daniela Chicco · Biella, IT
Giovanni Tesoriere · Noicattaro, IT
Clementina Brambati · Torino, IT

Key dates

Filing date	Oct 30, 2018
Grant date	Mar 24, 2020
Priority date	—
Expiry date	Oct 30, 2038

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K51/08
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to radionuclide complex solutions of high concentration and of high chemical stability, that allows their use as drug product for diagnostic and/or therapeutic purposes. The stability of the drug product is achieved by at least one stabilizer against radiolytic degradation. The use of two stabilizers introduced during the manufacturing process at different stages was found to be of particular advantage.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.