Patent · US Active

Preparation of certain substituted 1-(4-fluorophenyl)-4-(2,3,6b,9,10,10a-hexahydro-1H-pyrido[3′,4′:4,5]pyrrolo[1,2,3-de]quinoxalin-8(7H)-YL)butan-1-ones and pharmaceutically acceptable salts thereof

US10597395B2 · kind B2 · utility

18Cited by

57References

19Claims

0Family size

Assignee

INTRA-CELLULAR THERAPIES, INC. · US

Inventors

John Charles Tomesch · Succasunna, US
Peng Li · New York, US
Wei Yao · Shanghai, CN
Qiang Zhang · Dalian, CN
James David Beard · New York, US
Andrew S. Thompson · Mountainside, US
Hua Cheng · Plainsboro, US
Lawrence P. Wennogle · Fryeburg, US

Key dates

Filing date	Jan 10, 2019
Grant date	Mar 24, 2020
Priority date	—
Expiry date	Jan 10, 2039

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D471/04
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention provides methods for the preparation of certain optionally substituted heterocycle fused gamma-carbolines of Formula 2J, as shown below and as further defined herein:

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.