Protected monomer and method of final deprotection for RNA synthesis
US10597421B2 · kind B2 · utility
0Cited by
7References
17Claims
0Family size
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Key dates
| Filing date | Dec 12, 2017 |
| Grant date | Mar 24, 2020 |
| Priority date | — |
| Expiry date | Feb 2, 2038 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/55
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method of deprotecting a solid support bound polynucleotide comprising at least one 2′-protected ribonucleotide in which a step of contacting the polynucleotide with a composition comprising a diamine is performed under conditions sufficient to deprotect and cleave the polynucleotide which remains retained on the solid support.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.