Patent · US Active

T1R taste receptors and genes encoding same

US10597437B2 · kind B2 · utility

0Cited by
71References
10Claims
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Key dates

Filing dateOct 16, 2017
Grant dateMar 24, 2020
Priority date
Expiry dateOct 16, 2037

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N2333/726
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

Newly identified mammalian taste-cell-specific G protein-coupled receptors, and the genes and cDNA encoding said receptors are described. Specifically, T1R G protein-coupled receptors active in taste signaling, and the genes and cDNA encoding the same, are described, along with methods for isolating such genes and for isolating and expressing such receptors. Methods for representing taste perception of a particular taste stimulus in a mammal are also described, as are methods for generating novel molecules or combinations of molecules that elicit a predetermined taste perception in a mammal, and methods for simulating one or more tastes. Further, methods for stimulating or blocking taste perception in a mammal are also disclosed.

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